The mission of PTM Bio is to fundamentally transform the way we understand, diagnose, and treat human diseases by developing and using cutting-edge proteomics technology to examine profiles of proteins, histone epigenetic marks, and protein post-translational modifications. We integrate patient-derived proteomics information with genomics and trancriptomics data to identify biomarkers that can be used to diagnose diseases and predict drug sensitivity. Through discovery of therapeutic targets, identification of predictive biomarkers, and biomarker-guided drug discovery, we aim to make precision medicine a reality.


Since its founding in 2011, PTM Bio has built a leading mass spectrometry-based proteomics and epigenetics technology platform with exquisite sensitivity and accuracy. We are well positioned to apply state-of-the-art proteomics strategies in conjunction with next generation sequencing-based genomics and trancriptomics techniques to improve therapy selection for patients, and to discover a brave new world of medical possibilities.

  • We can definitively determine differential proteomic profiles (in terms of protein expression, protein modifications, and histone marks) comparing healthy and diseased patient samples to identify disease-relevant biomarkers, deregulated biological pathways, and novel therapeutic targets.


  • Building upon our expertise in identifying prognostic or predictive biomarkers, generating high-quality antibodies, and establishing multiplex assays using a variety of technology platforms, we will develop next-generation precision companion diagnostics to increase the safety and effectiveness of targeted therapies.


  • By applying our novel biomarker-guided drug discovery and clinical design strategies, we aim to develop effective and safe precision therapies to address unmet medical needs with significantly reduced cost, shortened cycle times, and improved efficiency relative to traditional drug development methods.


  • Leveraging our proteomics and reagent platforms, we provide state-of-the-art proteomics services and antibody reagents against specific histone marks and protein modifications.


PTM Biolabs is connected making us a click, or call, or shout away. With locations in the United States and China,our teams work seamlessly with our global customer base across all time zones. Our contract research team located in Hangzhou, China welcomes you for site visit anytime in our sq ft facilty. Our Chicago, Illinois team welcomes you anytime for brainstorming and problem solving. Our Boston team is always ready to come visit your site and help determine if proteomics can make a significant impact in your next project! Connect with us today!