PTMs and their corresponding effects on protein activity drive protein activities and function. Our understanding in the field of PTMs is largely hindered by the limited availability of high-quality antibodies against specific PTMs. PTMs antibodies are challenging to make and often have the insufficient specificity. Several reason contribute to the difficulty including subtle chemical difference, high-level similarity of sequence surrounding the different modification sites, and interference from unmodified protein sequence.
PTM offers a proprietary custom antibody generation service against ALL the PTMs that you can name it. Since 2010, we in-house produced over 250 PTM antibodies. Our custom antibody production service, includes: immunogen design & synthesis, immunization, antibody purification, and validation. Contact our Scientist TODAY to discuss your antibody needs for your PTM project here!