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  Zhang, Y., X. Wang, et al. (2016). “Proteomic and N-glycoproteomic quantification reveal aberrant changes in the human saliva of oral ulcer patients.” Proteomics. PMID:27763718  PTM Service  MS|IP  PTM
 Zhou, X., G. Qian, et al. (2016). “Systematic Analysis of the Lysine Acetylome in Candida albicans.” J Proteome Res 15(8): 2525-2536. PMID:27297460  PTM Service MS|IP PTM
Zheng, H., Y. He, et al. (2016). “Systematic Analysis of the Lysine Succinylome in Candida albicans.” J Proteome Res 15(10): 3793-3801. PMID:27605073 PTM Service MS|IP PTM
Guo, C., S. Xie, et al. (2016). “Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome.” Immunity. PMID: 27692610 Quantitative PTM Service MS|IP Customer
Wang, Z. K., J. Wang, et al. (2016). “Proteomic and Phosphoproteomic Insights into a Signaling Hub Role for Cdc14 in Asexual Development and Multiple Stress Responses in Beauveria bassiana.” PLoS One 11(4): e0153007. PMID: 27055109 Quantitative PTM Service  MS|IP  PTM
Li, L., L. Shi, et al. (2016). “SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability.” Nat Commun 7: 12235 PTM-114|PTM-401|PTM-105|PTM-402|PTM-503|PTM-904|Quantitative PTM Service IP|MS|WB PTM
Wang, T. Y., Y. R. Chai, et al. (2016). “Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells.” Oncotarget. PTM-104|Quantitative PTM service IP|MS PTM
Ruiz-Andres, O., M. D. Sanchez-Nino, et al. (2016). “Histone lysine crotonylation during acute kidney injury in mice.” Dis Model Mech 9(6): 633-645. PMID: 27125278  PTM-516|PTM-501 WB Client
Andrews, F. H., S. A. Shinsky, et al. (2016). “The Taf14 YEATS domain is a reader of histone crotonylation.” Nat Chem Biol 12(6): 396-398. PMID: 27089029    PTM-516  WB  Client
Goudarzi, A., D. Zhang, et al. (2016). “Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.” Mol Cell 62(2): 169-180. PMID: 27105113 PTM-310|PTM-311|PTM-301 WB|CHIP PTM
Qian, L., L. Nie, et al. (2016). “Global Profiling of Protein Lysine Malonylation in Escherichia coli Reveals Its Role in Energy Metabolism.” J Proteome Res. 15(6): 2060-2071. PMID: 27183143  

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Li, X., Q. Zhang, et al. (2016). “Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity.” Nat Immunol. PMID: 27240213  PTM Service MS PTM
Shen, Z., B. Wang, et al. (2016). “Global-scale profiling of differential expressed lysine acetylated proteins in colorectal cancer tumors and paired liver metastases.” J Proteomics 142: 24-32. PMID: 27178108 PTM Service MS Client
He et al. (2016). Global Proteome Analyses of Lysine Acetylation and Succinylation Reveal the Widespread Involvement of both Modification in Metabolism in the Embryo of Germinating Rice Seed. Journal of proteome research. PMID: 26767346  PTM-102|PTM-401|PTM-402|PTM Service WB|IP|MS PTM
Zhu et al. (2016). Quantitative Analysis of Global Proteome and Lysine Acetylome Reveal the Differential Impacts of VPA and SAHA on HL60 Cells. Scientific reports 6, 19926. PMID: 26822725 PTM-104|PTM Service|Protein Quantification Service IP|MS PTM
Xiong et al. (2016). A comprehensive catalog of the lysine-acetylation targets in rice (Oryza sativa) based on proteomic analyses. Journal of proteomics. PMID:26836501  PTM-104|PTM Service  IP|MS  PTM
Cheng et al. (2016). Quantitative succinylome analysis in the liver of non-alcoholic fatty liver disease rat model. Proteome science 14, 3. PMID:26843850  PTM-402|PTM-409  IP  Client
Jin, W., and Wu, F. (2016). Proteome-Wide Identification of Lysine Succinylation in the Proteins of Tomato (Solanum lycopersicum). PloS one 11, e0147586. PMID: 26828863  PTM-402|PTM-409  IP  Client
Goudarzi, A., D. Zhang, et al. (2016). “Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.” Mol Cell 62(2): 169-180. PMID: 27105113 PTM-301|PTM-311|PTM-313|PTM-105 WB|ChIP PTM
Li, Y., B. R. Sabari, et al. (2016). “Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.” Mol Cell 62(2): 181-193. PMID: 27105114 PTM-516|PTM-517|PTM-522 WB|ChIP Client
Xie, Z., D. Zhang, et al. (2016). “Metabolic Regulation of Gene Expression by Histone Lysine beta-Hydroxybutyrylation.” Mol Cell 62(2): 194-206. PMID: 27105115 PTM-1201|PTM-1220|PTM-1223|PTM-1300 WB|ChIP Client
Wang, Z. K., J. Wang, et al. (2016). “Proteomic and Phosphoproteomic Insights into a Signaling Hub Role for Cdc14 in Asexual Development and Multiple Stress Responses in Beauveria bassiana.” PLoS One 11(4): e0153007. PMID: 27055019 PTM Service|Protein Quant|Bioinformatics MS|Bioinformatics PTM
Xiong, Y., K. Zhang, et al. (2016). “Data for global lysine-acetylation analysis in rice (Oryza sativa).” Data Brief 7: 411-417. PMID: 26977447 PTM Service MS|Bioinformatics PTM
Gupta, N., M. P. Madapura, et al. (2015). “Mapping of Post-translational Modifications of Transition Proteins, TP1 and TP2, and Identification of Protein Arginine Methyltransferase 4 and Lysine Methyltransferase 7 as Methyltransferase for TP2.” J Biol Chem 290(19): 12101-12122. PMID: 25818198 PTM Service
Wu et al. (2015). A chemical proteomics approach for global analysis of lysine monomethylome profiling. Molecular & cellular proteomics 14, 329-339. PMID: 25505155  PTM-680|PTM-683|PTM Service  WB| IP|MS  PTM
Huang et al. (2015). Lysine acetylproteome analysis suggests its roles in primary and secondary metabolism in Saccharopolyspora erythraea. Applied microbiology and biotechnology 99, 1399-1413. PMID: 25487885  PTM-104  WB| IP  Clients
Xie et al. (2015). Proteome-wide lysine acetylation profiling of the human pathogen Mycobacterium tuberculosis. The international journal of biochemistry & cell biology 59, 193-202. PMID: 25456444  PTM-104|PTM Service  WB| IP|MS PTM
Yang et al. (2015). Succinylome Analysis Reveals the Involvement of Lysine Succinylation in Metabolism in Pathogenic Mycobacterium tuberculosis H37Rv. Molecular & cellular proteomics PMID: 25605462  PTM-401|PTM-402|PTM Service  WB| IP|MS  PTM
Mo et al. (2015). Acetylome Analysis Reveals the Involvement of Lysine Acetylation in Photosynthesis and Carbon Metabolism in the Model Cyanobacterium Synechocystis sp. PCC 6803. Journal of proteome research 14, 1275-1286. PMID: 25621733  PTM-104|PTM Service  WB| IP|MS  PTM
Du et al. (2015). Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins. Molecular & cellular proteomics : MCP 14, 227-236. PMID: 25418362  PTM-901  WB  Clients
Polletta et al. (2015). SIRT5 regulation of ammonia-induced autophagy and mitophagy. Autophagy 11, 253-270. PMID: 25700560  PTM-401  WB  Clients
Sabari et al. (2015). Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation. Molecular cell. PMID: 25818647  PTM-501|PTM-105|PTM-517  WB  Clients
Wu et al. (2015). Suberoylanilide hydroxamic acid treatment reveals crosstalks among proteome, ubiquitylome and acetylome in non-small cell lung cancer A549 cell line. Scientific reports 5, 9520. PMID: 25825284  PTM-1104|PTM Service|Protein Quantification Service  WB  PTM
Ouidir et al. (2015). Proteomic profiling of lysine acetylation in Pseudomonas aeruginosa reveals the diversity of acetylated proteins. Proteomics 15, 2152-2157. PMID: 25900529  PTM-104  WB| IP  Clients
Qian et al. (2015). Analyzing Arabidopsis thaliana root proteome provides insights into the molecular bases of enantioselective imazethapyr toxicity. Scientific reports 5, 11975. PMID: 26153126  Protein Quantification Service  MS Clients
Liu et al. (2015). Persistent human Borna disease virus infection modifies the acetylome of human oligodendroglia cells towards higher energy and transporter levels. Virology 485, 58-78. PMID: 26210075 PTM-104|PTM Service IP|MS PTM
Nie et al. (2015). Comprehensive profiling of lysine acetylation suggests the widespread function is regulated by protein acetylation in the silkworm, Bombyx mori. Proteomics. PMID: 26046922  PTM-104|PTM Service  IP|MS PTM
Colak et al. (2015) Proteomic and biochemical studies of lysine malonylation suggests its malonic aciduria-associated regulatory role in mitochondrial function and fatty acid oxidation.pii: mcp.M115.048850. PMID: 26320211 PTM-901|PTM Service IP|MS PTM
Chen, et al. (2015) Comparative phosphoproteomic analysis of intestinal phosphorylated proteins in active versus aestivating sea cucumbers. J Proteomics. PMID: 26385000 PTM Service MS Clients
Zhang et al. (2015) Comparative analysis of histone H3 and H4 post-translational modifications of esophageal squamous cell carcinoma with different invasive capabilities. J. Protoemics, 1;112:180-9. PMID: 25234497 PTM-105| PTM- 301 WB Clients
Boylston et al. (2015). Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury. Journal of molecular and cellular cardiology 88, 73-81. PMID: 26388266 PTM-401 WB Client
Singhal et al. (2015). Systematic analysis of mycobacterial acylation reveals first example of acylation-mediated regulation of enzyme activity of a bacterial phosphatase. The Journal of biological chemistry. PMID: 26350458 PTM-401|PTM-301 WB Client
Kwon et al. (2015). Global analysis of phosphoproteome dynamics in embryonic development of zebrafish (Danio rerio). Proteomics. PMID: 26449285 PTM Service MS PTM
Fang et al. (2015). Global analysis of lysine acetylation in strawberry leaves. Frontiers in plant science 6, 739. PMID: 26442052 PTM-105|PTM-104|PTM Service  WB|IP|MS  PTM
Wang et al. (2015). Suberoylanilide hydroxamic acid suppresses hepatic stellate cells activation by HMGB1 dependent reduction of NF-κB1. PeerJ 3, 1362. PMID:26557438 PTM-105 WB Client
Sin et al. (2015). Poised chromatin and bivalent domains facilitate the mitosis-to-meiosis transition in the male germline. BMC Biology. 13:53. PMID: 26198001  PTM-501  ChIP-seq  Client
Zhang et al. (2015). Comparative analysis of histone H3 and H4 post-translational modifications of esophageal squamous cell carcinoma with different invasive capabilities. Journal of proteomics 112, 180-189. PMID: 25234497  PTM-105|PTM-301  WB  Clients
Qi et al. (2014). Coordinated regulation of dendrite arborization by epigenetic factors CDYL and EZH2. The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 4494-4508. PMID: 24671995 PTM-101   WB   Clients
Lombard et al. (2014). Regulation of mitochondrial functions by SIRT5 and non-canonical post-translational modifications (LB172). FASEB, vol. 28 no. 1  PTM-105   WB   Clients
Zhang et al, Comprehensive Profiling of Lysine Acetylome in Staphylococcus aureus. Sci China Chem. In Press.  PTM-104  WB | IP   Clients
Liu et al. (2014). CPLM: a database of protein lysine modifications. Nucleic acids research 42, D531-536.  PTM Service  Bioinformatics Analysis  PTM
Tan et al. (2014). Lysine Glutarylation Is a Protein Posttranslational Modification Regulated by SIRT5. Cell metabolism 19, 605-617. PMID: 24703693  PTM-1151  WB | IP  Clients
Dai et al. (2014). Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark. Nature chemical biology 10, 365-370. PMID: 24681537  PTM-801|PTM-805  WB | IP  Clients
Liao et al. (2014). Unexpected extensive lysine acetylation in the trump-card antibiotic producer Streptomyces roseosporus revealed by proteome-wide profiling. Journal of proteomics 106, 260-269. PMID: 24768905  PTM-101|PTM Service  WB | IP |MS  PTM
Pan et al. (2014). Systematic analysis of the lysine acetylome in Vibrio parahemolyticus. Journal of proteome research 13, 3294-3302. PMID: 24874924  PTM-101|PTM Service  WB | IP |MS  PTM
Chen et al. (2014). Rapid Profiling of Proteomes and Sub-Proteomes on the Orbitrap Fusion Sub-proteomes on the Prbitrap Tribrid Mass Spectrometer. Thermofisher  PTM-104  WB | IP  Clients
Liu et al. (2014). Human borna disease virus infection impacts host proteome and histone lysine acetylation in human oligodendroglia cells. Virology 464-465, 196-205. PMID: 25086498  PTM-104|PTM-106|PTM-107|PTM-109|PTM-110|PTM-113|PTM-114|PTM-119|PTM-120  WB | IP  Clients
Pan et al. (2014). Systematic analysis of the lysine acetylome in Vibrio parahemolyticus. Journal of proteome research 13, 3294-3302. PMID: 24874924  PTM-104|PTM Service  WB | IP |MS  PTM
Xu et al. (2014). SAHA regulates histone acetylation, Butyrylation, and protein expression in neuroblastoma. Journal of proteome research 13, 4211-4219. PMID: 25160476  PTM-105|PTM-301|PTM-112|PTM-116|PTM-303|PTM-308  WB| IP  Clients
Xie et al. (2014). First Succinyl-Proteome Profiling of Extensively Drug-Resistant Mycobacterium tuberculosis Revealed Involvement of Succinylation in Cellular Physiology. Journal of proteome research. PMID: 25363132  PTM-104 WB| IP  Clients
Li et al. (2014). Systematic identification of the lysine succinylation in the protozoan parasite Toxoplasma gondii. Journal of proteome research 13, 6087-6095. PMID: 25377623  PTM-104|PTM-401|PTM Service  WB| IP|MS  PTM
Pougovkina et al. (2014). Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism. Journal of inherited metabolic disease. PMID: 24531926  PTM-201|PTM-301|PTM-901  WB   Clients
Bao et al. (2014). Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach. eLife 3. PMID: 25369635  PTM-501|PTM-515|PTM-516  WB  Clients
Gattner et al. (2013). Synthesis of epsilon-N-propionyl-, epsilon-N-butyryl-, and epsilon-N-crotonyl-lysine containing histone H3 using the pyrrolysine system. Chem Commun (Camb) 49, 379-381. PMID: 23192406  PTM-201|PTM-301|PTM-501  WB  Clients
Zhang et al. (2013). Comprehensive profiling of protein lysine acetylation in Escherichia coli. Journal of proteome research 12, 844-851.PMID: 23294111  PTM-101|PTM Service  WB|MS  PTM
Tannahill et al. (2013). Succinate is an inflammatory signal that induces IL-1beta through HIF-1alpha. Nature 496, 238-242. PMID: 23535595  PTM-401  WB   Clients
Lin et al. (2013). SIRT5 desuccinylates and activates SOD1 to eliminate ROS. Biochemical and biophysical research communications 441, 191-195. PMID: 24140062  PTM-401  WB   Clients
Weinert et al. (2013). Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation. Cell reports 4, 842-851. PMID: 23954790  PTM-401|PTM-402  WB   Clients
Yu et al. (2013). Metabolic characterization of a Sirt5 deficient mouse model. Scientific reports 3, 2806. PMID: 24076663   PTM-401 WB  Clients
Fritz et al. (2013). Ethanol metabolism modifies hepatic protein acylation in mice. PloS one 8, e75868. PMID: 24073283  PTM-101|PTM-201|PTM-301|PTM-401  WB  Clients
Wu et al. (2013). SAHA treatment reveals the link between histone lysine acetylation and proteome in nonsmall cell lung cancer A549 Cells. Journal of proteome research 12, 4064-4073. PMID: 23909948  PTM-106|PTM-107|PTM-109|PTM-110|PTM-119|PTM-122|PTM-164|PTM-112|PTM-115|PTM-116  WB  Clients
Yao et al. (2013). Detection and quantification of lysine acetyl-alteration using antibody microarray. Bioanalysis 5, 2469-2480. PMID: 24138621  PTM-101  WB  Clients
Wagner et al. (2013). Widespread and enzyme-independent Nepsilon-acetylation and Nepsilon-succinylation of proteins in the chemical conditions of the mitochondrial matrix. The Journal of biological chemistry 288, 29036-29045. PMID: 23946487  PTM-101|PTM-401  WB  Clients
Manuel te al. (2013). Adipocyte protein modification by Krebs cycle intermediates and fumarate ester-derived succination. Amino acids 45, 1243-1247. PMID: 23892396  PTM-401  WB  Clients
Nardelli et al. (2013). The histone code of Toxoplasma gondii comprises conserved and unique posttranslational modifications. mBio 4, e00922-00913. PMID: 24327343  PTM-401  WB  Clients
Park et al. (2013). SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Molecular cell 50, 919-930. PMID: 23806337  PTM-401  WB  Clients
Yang et al. (2013). Discovery Histone Deacetylase (HDAC) 6 Specific Proteomic Biomarker In Multiple Myeloma (MM) Using Stable Isotope Labeling By Amino Acids In Cell Culture (SILAC) Blood 122 (21).  PTM-105  WB  Clients
Chen et al. (2013). SILAC-based quantification of Sirt1-responsive lysine acetylome. Methods Mol Biol 1077, 105-120. PMID: 24014402  PTM-104 WB| IP   Clients
Montellier et al. (2013). Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B. Genes & development 27, 1680-1692.  PMID: 23884607  PTM-501  WB   Clients
Colak et al. (2013). Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Molecular & cellular proteomics : MCP 12, 3509-3520. PMID: 24176774  PTM-401   WB   Clients
Xie et al. (2012). Lysine succinylation and lysine malonylation in histones. Molecular & cellular proteomics 11, 100-107. PMID: 22389435  PTM-401|PTM-901  WB  PTM
Kim et al. (2012). Site-specific incorporation of epsilon-N-crotonyllysine into histones. Angew Chem Int Ed Engl 51, 7246-7249. PMID: 22689270  PTM-501  WB  Clients
Chen et al. (2012). Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Molecular & cellular proteomics 11, 1048-1062. PMID: 22826441  PTM-104|PTM Service  IP|MS  PTM
Sin et al. (2012). RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids. Genes & development 26, 2737-2748. PMID: 23249736  PTM-501  WB  Clients
Montellier et al. (2012). Histone crotonylation specifically marks the haploid male germ cell gene expression program: post-meiotic male-specific gene expression. BioEssays : news and reviews in molecular, cellular and developmental biology 34, 187-193. PMID: 22170506  PTM-501  WB  Clients
Cheng et al. (2009). Molecular characterization of propionyllysines in non-histone proteins. Molecular & cellular proteomics 8, 45-52. PMID 18753126. PTM-201|PTM Service WB|MS  PTM
Zhang et al. (2009). Identification and verification of lysine propionylation and butyrylation in yeast core histones using PTMap software. Journal of proteome research 8, 900-906. PMID: 19113941 PTM-301|PTM-201 WB Clients
Peng et al. (2011). The first identification of lysine malonylation substrates and its regulatory enzyme. Molecular & cellular proteomics 10, M111 012658. PMID: 21908771 PTM-901|PTM Service WB|MS PTM
Zhang et al. (2011). Identification of lysine succinylation as a new post-translational modification. Nature chemical biology 7, 58-63. PMID: 21151122  PTM-401 WB  Clients
Tan et al. (2011). Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell 146, 1016-1028.  PMID: 21925322  PTM-501  WB PTM
Lu et al. (2011). Bioinformatic analysis and post-translational modification crosstalk prediction of lysine acetylation. PloS one 6, e28228. PMID: 22164248  PTM-105|PTM Service  WB  PTM